PHARMACEUTICAL COMPOSITIONS FOR TRANSDERMAL ADMINISTRATION OF ANTI-INFLAMMATORY AGENTS

摘要

The invention concerns a pharmaceutical composition for transdermal administration comprising: a polymeric release matrix capable of forming a soft film after drying, selected among cellulose polymers or copolymers, said matrix being present at a concentration not exceeding 6 % of the composition weight; an active principle selected among the group of non-steroid anti-inflammatory agents comprising at least a metal carboxylic or carboxitate group; a transcutaneous absorption promoter of the active principle; water; and at least a physiologically acceptable non-aqueous solvent capable of dissolving the release matrix, the active principle and transcutaneous absorption promoter and to be rapidly eliminated by evaporation in contact with the skin.