发明名称 |
Controlled-release compositions containing opioid agonist and antagonist |
摘要 |
Controlled-release dosage forms containing an opioid agonist; an opioid antagonist; and a controlled release material release during a dosing interval an analgesic or sub-analgesic amount of the opioid agonist along with an amount of said opioid antagonist effective to attenuate a side effect of said opioid agonist. The dosage form provides analgesia for at least about 8 hours when administered to human patients. In other embodiments, the dose of antagonist released during the dosing interval enhances the analgesic potency of the opioid agonist.
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申请公布号 |
US2002010127(A1) |
申请公布日期 |
2002.01.24 |
申请号 |
US20010781076 |
申请日期 |
2001.02.08 |
申请人 |
OSHLACK BENJAMIN;WRIGHT CURTIS |
发明人 |
OSHLACK BENJAMIN;WRIGHT CURTIS |
分类号 |
A61K9/00;A61K9/16;A61K9/20;A61K9/50;A61K31/485;A61K38/33;(IPC1-7):A61K38/34 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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