OPTICAL COMPONENT BASED TEMPERATURE MEASUREMENT IN ANALYTE DETECTION DEVICES

摘要

Reflectance based methods and devices are provided for determining the concentration of an analyte in a fluid sample. In practicing the subject methods, a fluid sample is applied to a matrix impregnated with a signal producing system. Th e signal producing system produces a detectable product in an amount proportional to the amount of analyte in the sample. A surface of the matrix is then illuminated and a reflectance measurement is obtained therefrom, generally following a predetermined incubation period. An optical component, preferably the illumination or light detection means, is also employed to obtain a temperature value corresponding to the ambient temperature of th e matrix. The analyte concentration of the sample is then obtained from the reflectance measurement using an algorithm that employs the optical component derived temperature value. T he subject methods and devices are suited for use in the detection of a variety of different types of fluid analytes, and are particularly suited for use in detecting the concentration of glucose in whole blood.