发明名称 |
Methods for the preparation of 4-hydroxy benzothiophene |
摘要 |
The present invention is concerned with a novel process for the preparation of a hydroxybenzothiophene that is an intermediate for synthesizing pharmaceutically active substances, e.g. 5-[4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]-7-benzothiophenylmethyl]-2,4-thiazolidinedione and the corresponding sodium salt which are useful in the treatment of diabetes.
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申请公布号 |
US6482958(B2) |
申请公布日期 |
2002.11.19 |
申请号 |
US20010008877 |
申请日期 |
2001.11.08 |
申请人 |
HOFFMANN-LA ROCHE INC. |
发明人 |
JUNGHANS BERND;SCALONE MICHELANGELO;ZEIBIG THOMAS ALBERT |
分类号 |
C07D333/64;B01J31/22;B01J31/24;C07B61/00;C07D333/16;C07D333/54;C07D413/12;C07D417/14;(IPC1-7):C07D333/12;C07D333/24 |
主分类号 |
C07D333/64 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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