发明名称 |
Process for the preparation of cefpodoxime proxetil diastereoisomers |
摘要 |
A process for increasing the diastereoisomeric ratio (B/A+B), wherein B is the more apolar and A is the more polar of two diastereoisomers, of a mixture of diastereoisomers of a compound of formulathe diastereoisomers being with respect to the carbon atom marked with a star in formula I, comprising treating a mixture of diastereoisomers of a compound of formula I with alcohol and water and isolating the precipitated compound of formula I in an increased diastereoisomeric ratio (B/A+B) of 0.5 to 0.6.
|
申请公布号 |
US6489470(B1) |
申请公布日期 |
2002.12.03 |
申请号 |
US20000582896 |
申请日期 |
2000.08.21 |
申请人 |
BIOCHEMIE GESELLSCHAFT M.B.H. |
发明人 |
GREIL JULIA;LUDESCHER JOHANNES;TOTSCHNIG KLAUS;WOLF SIEGFRIED |
分类号 |
C07D501/12;C07D501/00;C07D501/34;(IPC1-7):C07D501/34 |
主分类号 |
C07D501/12 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|