发明名称 Pharmaceutical compositions containing triazolones and methods of treating neurodegenerative disease using triazolones
摘要 A method for treating a neurodegenerative disease or cerebral ischemia arising from conditions selected from the group consisting of Status epilepticus, hypoglycaemia, hypoxia, anoxia, brain trauma, brain oedema, amyotropic lateral sclerosis, Huntington's disease, Alzheimer's disease, hypotonia, cardiac infarction, brain pressure (elevated intracranial pressure), ischaemic and haemorrhagic stroke, global cerebral ischaemia with heart stoppage, diabetic polyneuropathy, tinnitus, perinatal asphyxia, psychosis, schizophrenia, depression, and Parkinson's disease, the method of treatment comprising administering to a host in need of such treatment a therapeutic amount of a compound of formula (I)wherein R1, R2, R3, R4, R5, R6, and R7 are as defined herein, or a pharmaceutically acceptable salt thereof, and pharmaceutical compositions containing a compound of formula (I).
申请公布号 US6492407(B2) 申请公布日期 2002.12.10
申请号 US20010840281 申请日期 2001.04.23
申请人 BOEHRINGER IMGELHEIM PHARMA KG 发明人 BRENNER MICHAEL;BECHTEL WOLF-DIETRICH;PALLUK RAINER;WIENRICH MARION;WEISER THOMAS
分类号 A61K31/41;A61K31/4427;A61K31/4439;A61P9/10;A61P25/00;C07D249/12;C07D401/04;(IPC1-7):A61K31/41 主分类号 A61K31/41
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