发明名称 |
nucleic acid sequences encoding methylation and carbamoylation enzymes involved in mitomycin biosynthesis |
摘要 |
The invention provides a biosynthetic gene cluster for mitomycin, for example, a mitomycin biosynthetic cluster from organisms such as Streptomyces, for instance, S. lavendulae, as well as methods of using gene(s) within the cluster to alter antibiotic biosynthesis and to prepare a polyketide synthase.
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申请公布号 |
US6495348(B1) |
申请公布日期 |
2002.12.17 |
申请号 |
US19990266965 |
申请日期 |
1999.03.12 |
申请人 |
REGENTS OF THE UNIVERSITY OF MINNESOTA |
发明人 |
SHERMAN DAVID H.;MAO YINGQING;VAROGLU MUSTAFA;HE MIN;SHELDON PAUL |
分类号 |
C07K14/36;C12N1/21;C12N9/00;C12N9/02;C12N9/10;C12N9/12;C12N9/14;C12N9/88;C12N15/52;C12P17/18;C12Q1/68;(IPC1-7):C12P19/62 |
主分类号 |
C07K14/36 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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