SMALL MOLECULE MODULATION OF RIBOZYMES

摘要

A method for selecting a compound that modulates the activity of a ribozyme in vivo in an organism comprising: (a) measuring in an assay the ability of a compound to selectively bind to a ribozyme thereby inhibiting the function of said ribozyme; and (b) selecting the assayed compound for use in modulating the activity of said ribozyme in vivo in an organism as a pharmaceutical agent as well as a method for selecting a compound for diagnosing the presence of a ribozyme in an organism that is pathogenic to an animal or plant.