| 发明名称 |
Antitumorforbindelser, farmaceutiske præparater, fremgangsmåder til fremstilling deraf og til behandling |
| 摘要 |
<p>The present invention is directed to novel taxanes useful as chemotherapeutic agents or their precursors. Processes for preparing the novel taxanes include coupling reactions, in the presence of a base, of baccatin of formula (III) or (IV) <IMAGE>rmula (V). <IMAGE> (V) The invention also provides pharmaceutical compositions including the novel taxanes and method for treatment of certain cancers with these new compounds.</p> |
| 申请公布号 |
DK0690856(T3) |
申请公布日期 |
2003.03.31 |
| 申请号 |
DK19940912300T |
申请日期 |
1994.03.24 |
| 申请人 |
INDENA S.P.A.;THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK |
发明人 |
OJIMA, IWAO;BOMBARDELLI, EZIO |
| 分类号 |
A61K31/00;A61K31/335;A61K31/337;A61P35/00;C07D205/08;C07D305/14;C07F7/18;(IPC1-7):C07D409/00;C07D205/00;C07D405/00;C07D315/00;C07D307/02;C07D213/02;C07D207/08;C07D413/00;C07D493/08;C07D203/04;C07D407/00 |
主分类号 |
A61K31/00 |
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