发明名称 |
Compounds and methods for modulating adhesion molecule function |
摘要 |
Modulating agents and methods for enhancing or inhibiting cadherin-mediated functions are provided. The modulating agents comprise at least an HAV binding motif, an analogue or peptidomimetic thereof, or an antibody or fragment thereof that specifically binds to such a motif. Modulating agents may additionally comprise one or more cell adhesion recognition sequences recognized by cadherins and/or other adhesion molecules. Such modulating agents may, but need not, be linked to a targeting agent, drug and/or support material.
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申请公布号 |
US2003109454(A1) |
申请公布日期 |
2003.06.12 |
申请号 |
US20020193653 |
申请日期 |
2002.07.10 |
申请人 |
ADHEREX TECHNOLOGIES, INC. |
发明人 |
DOHERTY PATRICK;BLASCHUK OREST W.;GOUR BARBARA J. |
分类号 |
C12N15/09;A61K38/00;A61K39/395;A61K47/48;A61P17/02;A61P25/00;A61P35/00;A61P43/00;C07K7/06;C07K7/64;C07K14/705;C07K16/18;(IPC1-7):A61K38/10;A61K38/08;C07K7/08 |
主分类号 |
C12N15/09 |
代理机构 |
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地址 |
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