| 发明名称 |
Methods for specifically inhibiting histone deacetylase-4 |
| 摘要 |
This invention relates to the inhibition of histone deacetylase (HDAC) expression and enzymatic activity. The invention provides methods and reagents for inhibiting HDAC-4 and HDAC-1 by inhibiting expression at the nucleic acid level or inhibiting enzymatic activity at the protein level.
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| 申请公布号 |
US2003148970(A1) |
申请公布日期 |
2003.08.07 |
| 申请号 |
US20020052390 |
申请日期 |
2002.01.14 |
| 申请人 |
BESTERMAN JEFFREY M.;BONFILS CLAIRE;LI ZUOMEI;WOO SOON HYUNG;VAISBURG ARKADII;DELORME DANIEL;FOURNEL MARIELLE;LAVOIE RICO |
发明人 |
BESTERMAN JEFFREY M.;BONFILS CLAIRE;LI ZUOMEI;WOO SOON HYUNG;VAISBURG ARKADII;DELORME DANIEL;FOURNEL MARIELLE;LAVOIE RICO |
| 分类号 |
A61K31/167;A61K31/18;A61K31/4035;A61K31/4418;A61K31/711;C12N5/02;(IPC1-7):A61K48/00 |
主分类号 |
A61K31/167 |
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