发明名称 NOVEL NAPHTHYLSULFONIC ACIDS AND RELATED COMPOUNDS AS GLUCOSE UPTAKE AGONISTS
摘要 Methods for treating conditions associated with hyperglycemia, especially Type II diabetes, with novel naphthylsulfonic acids and related compounds. These compounds, as single stereoisomers or mixtures of stereoisomers, or their pharmaceutically acceptable salts, are useful in methods of stimulating the kinase activity of the insulin receptor, enhancing the activation of the insulin receptor by insulin, and stimulating the uptake of glucose into cells. A variety of antidiabetic compounds and pharmaceutical compositions comprising the antidiabetic compounds are also disclosed.
申请公布号 PL353359(A1) 申请公布日期 2003.11.17
申请号 PL20000353359 申请日期 2000.07.28
申请人 TELIK,INC. 发明人 SPEVAK WAYNE R.;SONGYUAN SHI;PRASAD V.V.S.V.MANCHEM;KOZLOWSKI MICHAEL R.;SCHOW STEVEN R.;LUM ROBERT T.;ROBINSON LOUISE;PARK JEONG WEONG
分类号 C07D215/40;A61K31/167;A61K31/18;A61K31/192;A61K31/198;A61K31/341;A61K31/343;A61K31/4409;A61K31/455;A61K31/47;A61K31/498;A61P3/10;A61P43/00;C07C237/42;C07C309/51;C07C309/59;C07C311/13;C07C311/21;C07C311/29;C07C311/46;C07D213/81;C07D213/82;C07D215/48;C07D241/44;C07D307/68;C07D307/85 主分类号 C07D215/40
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