发明名称 |
IMMUNOTHERAPEUTIC COMBINATIONS FOR TREATING CANCERS OVEREXPRESSING GANGLIOSIDES |
摘要 |
The invention relates to the immunology, in particular to the immunotherapeutic combinations used for controlling the growth and/or proliferation of cancer cells. The anticancer effect is provided by ganglioside vaccine, namely murine monoclonal antibody (Ab1) against gangliosides and idiotypic vaccine, namely murine idiotypic antibody (Ab2) against antiganglioside antibody. The combination of these vaccines providing for the synergistic effect is disclosed. The said combinations may be advantageous for treating cancers overexpressing gangliosides. |
申请公布号 |
UA76745(C2) |
申请公布日期 |
2003.12.15 |
申请号 |
UA20030108988 |
申请日期 |
2002.04.08 |
申请人 |
CENTRO DE INMUNOLOGIA MOLECULAR |
发明人 |
FERNANDEZ MOLINA LUIS ENRIQUE;VAZQUEZ LOPEZ ANA MARIA;ROJAS DEL CALVO ADRIANA MARIA |
分类号 |
C12N15/09;A61K31/7032;A61K31/739;A61K39/00;A61K39/395;A61P35/00;A61P35/04;A61P37/00;A61P37/04;A61P43/00;C07K16/00;C07K16/18;C07K16/30;C07K16/42;C07K16/46;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N5/20;C12P21/08 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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