СПОСОБ СИНТЕЗА ПРОМЕЖУТОЧНОГО СОЕДИНЕНИЯ ДЛЯ ПОЛУЧЕНИЯ ЭКТЕИНАСЦИДИНА И ФТАЛАСЦИДИНА

摘要

An efficient process is described for the synthesis of 5, a key intermediate for the synthesis of the potent antitumor agents ecteinascidin 743 (1) and phthalascidin (2) from the readily available building blocks 3b and 4.