发明名称 ISOINDOLE-IMIDE COMPOUNDS, COMPOSITIONS, AND USES THEREOF.
摘要 <p>The invention relates to a isoindole-imide compound of formula I-4 comprising compound. The compound I-4 is a potent inhibitor of the production of the TNF-± in mammals, and thus useful for treating or preventing diseases or disorders in mammals, for example, cancers, such as solid tumors and blood-born tumors; heart disease, such as congestive heart failure; osteoporosis; and genetic, inflammatory, allergic, and autoimmune diseases.</p>
申请公布号 MXPA03005786(A) 申请公布日期 2004.01.26
申请号 MX2003PA05786 申请日期 2001.12.21
申请人 CELGENE CORPORATION 发明人 GEORGE W. MULLER
分类号 C07D401/02;A61K31/44;A61K31/454;A61P1/04;A61P9/00;A61P9/10;A61P11/00;A61P17/06;A61P19/02;A61P29/00;A61P35/00;A61P37/00;A61P43/00;C07D401/04;C07D401/14;C07D405/14;C07D409/14;(IPC1-7):A61K31/44;A61K31/445;A61K31/495;C07D407/14 主分类号 C07D401/02
代理机构 代理人
主权项
地址