| 发明名称 |
EP4 RECEPTOR INHIBITORS TO TREAT RHEUMATOID ARTHRITIS |
| 摘要 |
<p>The invention features a method of treating rheumatoid arthritis in a mammal comprising administering an agent that inhibits prostaglandin EP4 receptor (EP4) activity. Also featured is a method of identifying agents that selectively inhibit EP4 activity in vivo. 6 claims, 7 figures</p> |
| 申请公布号 |
BG107732(A) |
申请公布日期 |
2004.01.30 |
| 申请号 |
BG20030107732D |
申请日期 |
2003.04.16 |
| 申请人 |
PFIZER INC. |
发明人 |
AUDOLY, LAURENT P.;OKUMURA, TAKAKO;SHIMOJO, MASATO |
| 分类号 |
G01N33/48;A61K31/00;A61K31/4178;A61K31/4184;A61K31/4188;A61K31/427;A61K31/437;A61K31/4439;A61K31/444;A61K31/454;A61K31/4725;A61K31/506;A61K31/52;A61K31/64;A61K45/00;A61P1/00;A61P1/02;A61P1/04;A61P3/10;A61P5/00;A61P7/02;A61P7/04;A61P7/08;A61P9/00;A61P9/10;A61P9/12;A61P9/14;A61P11/02;A61P11/06;A61P13/12;A61P15/04;A61P15/06;A61P17/00;A61P17/02;A61P17/16;A61P19/02;A61P19/06;A61P19/08;A61P19/10;A61P21/00;A61P25/00;A61P25/02;A61P25/04;A61P25/06;A61P25/20;A61P25/28;A61P27/00;A61P27/06;A61P29/00;A61P31/12;A61P31/16;A61P31/18;A61P35/00;A61P35/04;A61P37/00;A61P37/02;A61P37/06;A61P37/08;A61P41/00;A61P43/00;C07D235/06;C07D235/08;C07D235/10;C07D235/12;C07D235/14;C07D235/16;C07D235/30;C07D401/04;C07D401/06;C07D401/12;C07D403/04;C07D403/06;C07D403/12;C07D413/12;C07D417/04;C07D417/12;C07D471/04;C07D473/00;C07D491/04;C07D491/048;C07D491/056;C07D521/00;G01N33/15;G01N33/50;(IPC1-7):A61K31/417 |
主分类号 |
G01N33/48 |
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