| 摘要 |
THERE IS PROVIDED TRIPEPTIDE COMPOUNDS OF FORMULA I, WHEREIN P, Q, R 1, R2, R3, R4, Y, N AND B HAVE MEANINGS GIVEN IN THE DESCRIPTION WHICH ARE USEFUL AS COMPETITIVE INHIBITORS OF TRYPSIN-LIKE PROTEASES, SUCH AS THROMBIN, AND IN PARTICULAR IN THE TREATMENT OF CONDITIONS WHERE INHIBITION OF THROMBIN IS REQUIRED (EG THROMBOSIS) OR AS ANTICOAGULANTS.
|
