| 摘要 |
<p>Novel compounds of formula (I), with the exception of i) the racemate of (3 amino 2 hydroxypropyl)methylphosphinic acid; ii) S (3 amino 2 hydroxypropyl)methylphosphinic acid; iii) R (3 amino 2 hydroxypropyl)methylphosphinic acid; iv) (3 amino 2 hydroxypropyl)difluoromethylphosphinic acid; and v) (3 amino 2 oxopropyl)methylphosphinic acid, having affinity to one or more GABAB receptors, their pharmaceutically acceptable salts, solvates and stereoisomers, as well as a process for their preparation, pharmaceutical compositions containing said therapeutically active compounds and the use of said active compounds in therapy.</p> |
