| 摘要 |
PROBLEM TO BE SOLVED: To provide a new compound useful for treating abnormal cell growth. SOLUTION: The invention relates to the compound of formula (1). (In the formula, X is N or CH, A a condensed 5, 6 or 7 membered ring or the like R<SP>1</SP>and R<SP>2</SP>are each a 1-6C alkyl, R<SP>4</SP>is a -(CR<SP>1</SP>R<SP>2</SP>)<SB>m</SB>-C≡C-(CR<SP>1</SP>R<SP>2</SP>)<SB>t</SB>R<SP>9</SP>, etc., or R<SP>4</SP>is -(CR<SP>1</SP>R<SP>2</SP>)<SB>m</SB>-C≡C-(CR<SP>1</SP>R<SP>2</SP>)<SB>k</SB>R<SP>13</SP>or the like), for example, (+)-(3-methyl-4-phenoxy-phenyl)-(6-piperidin-3(R)-ylethnyl-quinazolin-4-yl)-amine, 3-(S)-[4-(3-methyl-4-phenoxy-phenylamino)-quinazolin-6-ylethynyl]-piperidine-1-carboxylic acid methylamide. COPYRIGHT: (C)2005,JPO&NCIPI |
