发明名称 Metal compounds, mixed or sulphated, as phosphate binders
摘要 A non-aluminum containing mixed metal compound for pharmaceutical use, which may, for example, be a mixed metal hydroxy carbonate containing magnesium and iron, and may have a hydrotalcite structure, preferably a non-aged hydrotalcite structure. Other metals, including, for example, calcium, lanthanum and cerium, may also be used. Metal sulphate compounds, especially calcium sulphate, lanthanum sulphate and/or cerium sulphate, compounds are also useful. The mixed metal compounds have a phosphate binding capacity of at least 30%, by weight, based on the test methods 1, 2 or 3, described in the specification, over a pH range from 3 to 7, such as from 2 to 8. The compound is especially useful in the treatment of hyperphosphataemia.
申请公布号 US6926912(B1) 申请公布日期 2005.08.09
申请号 US20000508923 申请日期 2000.06.19
申请人 INEOS SILICAS LIMITED 发明人 ROBERTS NORMAN B;WEBB MAURICE;RANKIN BENJAMIN J
分类号 A61K33/08;A61K33/24;A61K33/26;A61K45/06;A61P3/12;C01G49/00;(IPC1-7):A61K33/26;C01B31/24;C01G49/02 主分类号 A61K33/08
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