METHODS AND COMPOSITIONS FOR THE DETECTION OF NITRIC OXIDE

摘要

A method of detecting S-nitrosylated proteins or peptides in a biological sample, said method comprising: photolytically cleaving S-nitrosothiols in said S-nitrosylated proteins or peptides to form thiyl radical groups; contacting said biological sample with a thiyl radical-reacting compound, said thiyl radical-reacting compound modified with at least one marker; and detecting said marker with an appropriate detecting device.