发明名称 QUINAZOLINE DERIVATIVES AS SRC TYROSINE KINASE INHIBITORS
摘要 The invention concerns quinazoline derivatives of Formula (I): (A chemical formula should be inserted here-please see paper copy enclosed herewith) wherein Z is an O, S, SO, SO2, N(R2) or C(R2)2 group wherein each R2 group is hydrogen or (1-8C) alkyl, m is 0, 1, 2 or 3, each R1 group is selected from halogeno, (1-8C) alkyl, (1-6C) alkoxy and any of the other meanings defined in the description, n is 0, 1, 2 or 3, and each R3 group is selected from halogeno, (1-8C) alkyl, (1-6C) alkoxy and any of the other meanings defined in the description, or pharmaceutically-acceptable salts thereof, processes for their preparation, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use as an anti-invasive agent in the containment and/or treatment of solid tumor disease.
申请公布号 PL376255(A1) 申请公布日期 2005.12.27
申请号 PL20030376255 申请日期 2003.10.29
申请人 ASTRAZENECA AB 发明人 PLE PATRICK
分类号 A61K31/517;A61P35/00;C07D491/04;C07D519/00 主分类号 A61K31/517
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