| 主权项 |
1. A tissue ablation device comprising:
a probe comprising a nonconductive elongated shaft having a proximal end and a distal end and at least one lumen extending therethrough; an expandable balloon assembly coupled to the distal end of the probe shaft, the expandable balloon assembly comprising:
an expandable inner balloon comprising an inner balloon wall having an interior surface and a lumen defined therein and in fluid connection with at least one lumen of the probe, the inner balloon wall further having an exterior surface having an irregular surface defined thereon, wherein the inner balloon is configured to inflate into an expanded configuration in response to delivery of a first fluid from at least one lumen of the probe into the lumen of the inner balloon;an expandable outer balloon surrounding the inner balloon and configured to transition to an expanded configuration in response expansion of the inner balloon, the outer balloon comprising an outer balloon wall having an interior surface, an exterior surface, and a chamber defined between the interior surface of the outer balloon and the exterior surface of the inner balloon, wherein the chamber is in fluid connection with at least one lumen of the probe, the outer balloon wall further comprising plurality of perforations configured to allow the passage of a second fluid from the chamber to the exterior surface of the outer balloon upon delivery of the second fluid from at least one lumen of the probe into the chamber; and an electrode array comprising a plurality of conductive wires positioned within the chamber between the exterior surface of the inner balloon wall and the interior surface of the outer balloon wall, each of the plurality of conductive wires is configured to conduct energy to be carried by the fluid within the chamber from the interior surface to the exterior surface of the outer balloon wall for ablation of a target tissue. |
