摘要 |
Tetracycline or a tetracycline derivative such as oxytetracycline or chlortetracycline may be rendered water-soluble by complexing it with a methyleneamino-salicylate or methyleneamino-salicylic acid and then separating and purifying the complex so formed. The complexing step is generally carried out in an inert atmosphere, in the absence of light and in the presence of methyl alcohol as solvent.
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