发明名称 WATER-SOLUBLE TETRACYCLINES
摘要 Tetracycline or a tetracycline derivative such as oxytetracycline or chlortetracycline may be rendered water-soluble by complexing it with a methyleneamino-salicylate or methyleneamino-salicylic acid and then separating and purifying the complex so formed. The complexing step is generally carried out in an inert atmosphere, in the absence of light and in the presence of methyl alcohol as solvent.
申请公布号 US3846486(A) 申请公布日期 1974.11.05
申请号 US19700045267 申请日期 1970.06.10
申请人 MARCUS I,NL 发明人 MARCUS I,NL
分类号 A61K47/18;(IPC1-7):C07C103/19 主分类号 A61K47/18
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