发明名称 |
BENZENESULFONYLUREA DERIVATIVES |
摘要 |
Several novel benzenesulfonylurea compounds derived from 4-methyl-5-thiazolecarboxylic acid have been prepared by reacting 4-[2-(4-methyl-5-thiazolecarboxamido)ethyl]benzenesulfonamide with an appropriate organic isocyanate or a trisubstituted urea equivalent thereof. The sulfonylureas so obtained are useful in therapy as oral hypoglycemic agents. 1-Cyclohexyl-3-{4-[2-(4-methyl-5-thiazolecarboxamido)ethyl]benzenesulf onyl}urea represents a preferred embodiment. |
申请公布号 |
AU6586474(A) |
申请公布日期 |
1975.03.06 |
申请号 |
AU19740065864 |
申请日期 |
1974.02.21 |
申请人 |
PFIZER INC. |
发明人 |
HANS EBERHARD WIEDERMANN;REINHARD SARGES;DONALD ERNEST KUHLA |
分类号 |
C07D277/20;A61K31/425;A61K31/426;A61P3/08;A61P3/10;C07C311/59;C07D277/54;C07D277/56 |
主分类号 |
C07D277/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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