摘要 |
1430558 Inosine-5<SP>1</SP>-monophosphate; microorganisms AJINOMOTO CO Inc 8 Oct 1974 [12 Oct 1973] 43634/74 Heading C2P Inosine-5<SP>1</SP>-monophosphate is produced by culturing a hypoxanthine-requiring microorganism of the genus Corynebacterium in an aqueous culture medium containing assimilable sources of C and N, inorganic ions, minor organic nutrients necessary for the growth of the microorganism, phosphate ions and ionsine and/or hypoxanthine, until inosine-5<SP>1</SP>-monophosphate accumulates in the culture medium. The microorganism is preferably resistant to 8-azaguanine and may be an artificially induced mutant of Corynebacterium sp. ATCC 21251, morphological details of which are given in U.K. patent Specification No. 1,188,885. Specified suitable mutants are Corynebacterium sp. FERM-P 2310 and FERM-P 2311, which are claimed per se.
|