| 摘要 |
1490886 Acrylic polymer beads NATIONAL AERONAUTICS & SPACE ADMINISTRATION 17 Jan 1975 [17 Jan 1974] 2144/75 Heading C3P At least 80% of the hydrophilic, cross linked round beads of a cross-linked polymer prepared from an acrylic monomer containing a hydroxyl, carboxyl or amino group, and 0À1-30% of a diene or triene cross linking agent, have a diameter not greater than 2 microns. They may be prepared by polymerization of the monomer with its cross linking agent in an aqueous medium containing 0À05-5% of a watersoluble polyether. In the examples impure hydroxyethylmethacrylate, acrylamide, and dimethylaminoethyl methacrylate were polymerized using ethylene dimethacrylate, trimethylol propane trimethacrylate, and N,N<SP>1</SP>- methylene-bis acrylamide as cross linking agents and polyethylene oxide as the polyether. The products of the invention may be used in the separation of molecules, and in various analytical and diagnostic techniques. In Examples 6 and 7, beads of a hydroxethylmethacrylate / trimethylolpropane trimethylacrylate copolymer are activated with cyanogen bromide and then reacted with, respectively, epsilon dansyl lysine or 9-aminoacridine hydrochloride to give fluorescent products. |
