| 摘要 |
<p>1420912 Process for 2,5-disubstituted benzamides SOC D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE - DEFRANCE 1 March 1974 [5 March 1973] 9426/74 Heading C2C The invention comprises a process for making compounds (I): (in which A is a mono- or di-C 1-5 alkylamino radical or a heterocyclic saturated ring containing nitrogen, oxygen and/or sulphur as hetero atom(s); B is a C 1-5 alkyl radical or an alkenyl radical; n is 1 or 2, and X is an amino, monoalkylamino, dialkylamino, alkyl or alkenyl radical), their addition salts with pharmaceutically acceptable inorganic or organic acids, and their quaternary ammonium salts, by treating a corresponding 2,5-disubstituted benzoic acid with H 2 N(CH 2 ) n A in the presence of SiCl 4 , and, if desired, converting a product obtained into its salt.</p> |
