ANTI-INFLAMMATORY THIAZOLE COMPOSITIONS AND METHODS FOR USING SAME

摘要

1407856 And-inflammatory compounds UNIROYAL INC and UNIROYAL LTD 21 Nov 1972 [22 Nov 1971] 53708/72 Heading A5B Anti-inflammatory preparations comprise compounds of formula: or acid solution salts thereof wherein R is C 1-4 alkyl or N-amino-carbomoyl, R' is -CONHR 1 , or -CONR 2 R 3 , R" and R'" are H, C 1-4 alkyl or C 1-4 acyl, R 1 is phenyl optionally substituted with up to 3 C 1-4 alkyl groups, benzyl, halophenyl, cyclohexyl or amino, R 2 is C 1-4 alkyl, R 3 is C 1-4 alkyl or phenyl or R 2 and R 3 together with the nitrogen atom to which they are attached represent morpholino, R 4 is C 1-4 alkyl and R 5 is H, -CONHC 6 H 5 or -CONHC 6 H 3 (C 2 H 5 ) 2 . The preparations may take the form of pills, tablets, capsules, solutions or suspensions, injectable forms and ointments.