摘要 |
1529463 Pyrans SMITHKLINE CORP 13 Oct 1975 [11 Nov 1974] 41844/75 Heading C2C [Also in Division A5] Substituted 4,6-dihydroxy-2H-pylon-2-ones of the formula wherein R is C 1-6 straight or branched chain alkyl, the R's being identical are prepared by reacting acetonedicarboxylic acid and an appropriate acid anhydride of formula where R is as defined above. The compounds inhibit the antigen-antibody reaction and are useful in the treatment of allergic diseases such as asthma, rhinitis and urticaria. |