Provided herein are methods and devices for the detection of analytes. The methods employ particles formed from a first metal conjugated to analytes. The analyte conjugated to the particle formed from the first metal can be accumulated at a working electrode. The first metal can be galvanically exchanged with ions of a second metal to form a layer of the first metal at the working electrode. The first metal can then be electrochemically detected and/or quantified. Using this method, analytes can be detected at low concentrations a few femtomolar via anodic stripping voltammetry, with no washing steps or electrode modifications.
申请公布号
WO2016164738(A1)
申请公布日期
2016.10.13
申请号
WO2016US26665
申请日期
2016.04.08
申请人
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
发明人
CROOKS, Richard M.;RICHARDS, Ian;CUNNINGHAM, Josephine;KOGAN, Molly;TSAI, Yi-Ju;LUO, Long