Aminopropanol compounds and compositions for the treatment of cardiac and circulatory diseases

摘要

New aminopropanol compounds of the formula <IMAGE> (I) wherein R is lower alkyl, cycloalkyl or alkylthioalkyl, R1 is hydrogen or lower alkyl, hydroxyalkyl, pivaloyloxyalkyl, alkoxyalkyl, alkoxycarbonyl, carboxyl or -CONR3R4, in which R3 and R4 which can be the same or different, represent hydrogen or lower alkyl, and R2 is lower alkyl, hydroxyalkyl, alkoxyalkyl or pivaloyloxyalkyl or, when R is alkylthioalkyl or R1 is pivaloyloxyalkyl, R2 can also be hydrogen and the pharmacologically acceptable salts thereof; ARE OUTSTANDINGLY EFFECTIVE IN THE TREATMENT OR PROPHYLAXIS OF CARDIAC AND CIRCULATORY DISEASES.