发明名称 IMIDAZO[1,2-b][1,2,4]TRIAZINES AS c-Met INHIBITORS
摘要 The present invention relates to imidazo[1,2-b][1,2,4]triazines which are 2-fluoro-N-[(2R)-2-hydroxypropyl]-4-[7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide or 2-chloro-N-[(1S)-1-(5-methyl-1,2,4-oxadiazol-3-yl)ethyl]-4-[7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide; or to pharmaceutically acceptable salts of any of the above stated compounds, that are inhibitors of c-Met and are useful in the treatment of c-Met associated diseases including cancer.
申请公布号 EA025304(B1) 申请公布日期 2016.12.30
申请号 EA20120090744 申请日期 2011.02.02
申请人 INCYTE HOLDINGS CORPORATION 发明人 ZHUO Jincong;HE Chunhong;YAO Wenqing
分类号 C07D487/04;A61K31/53;A61P1/00;A61P9/00;A61P11/00;A61P29/00;A61P35/00;A61P37/00 主分类号 C07D487/04
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