发明名称 NOVEL CYCLIC AZABENZIMIDAZOLE DERIVATIVES USEFUL AS ANTI-DIABETIC AGENTS
摘要 Novel compounds of structural formula (I), wherein R, T, U, V, W, X, Y and Z are disclosed in the claims, are activators of AMP-protein kinase and are useful in the treatment, prevention and suppression of diseases mediated by the AMPK-activated protein kinase. The compounds of the present invention are useful in the treatment of Type 2 diabetes, hyperglycemia, metabolic syndrome, obesity, hypercholesterolemia, and hypertension.
申请公布号 EA025380(B1) 申请公布日期 2016.12.30
申请号 EA20130091236 申请日期 2012.02.23
申请人 MERCK SHARP & DOHME CORP. 发明人 ANAND Rajan;APGAR James, M.;BIFTU Tesfaye;CHEN Ping;CHU Lin;COLANDREA Vincent, J.;DONG Guizhen;DROPINSKI James, F.;FENG Danqing;HICKS Jacqueline, D.;JIANG Jinlong;KIM Alexander, J.;LEAVITT Kenneth, J.;LI Bing;QIAN Xiaoxia;SEBHAT Iyassu;WEI Lan;WILKENING Robert, R.;WU Zhicai
分类号 A01N43/58 主分类号 A01N43/58
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