| 摘要 |
Derivatives of p-alkyl-carbonyl-phenoxy-alkyl- and carboxy-phenoxy-alkyl-carboxylic acids complying to the general formula: R-C-O-CH-(CH2)n-C-Y PARALLEL ¦ PARALLEL XR'O where R represents -H, NH2; (-CH3C2H5, C3H7, or the omega halogen derivatives of these groups); C6H5; -OH, -OCH3, OC2H5, NHOH or R1 N ANGLE R2 where R1 and R2 can be linear radicals such as -CH3 or -CH2-CH3 or can be a ring such as that of piperidine, methyl-2-piperidine, piperazine, morpholine, pyrrolidine, methyl-4-piperidine, N-phenyl-piperazine, N-p-methoxy-phenyl-piperazine, N-methyl-4-piperazine, N-p-chlorophenyl-piperazine or hexamethyleneimine or ethylamino-ethyl-amine; X represents =O or =N-O-H; R-C- represents -C 3BOND N; n is 0, 1, 2 or 3 normal or iso when R' is -H and N IS 1, 2, 3 WHEN R' is -C6H5; R' represents -H or C6H5; and Y represents -OH -OCH3; -OC2H5; NHOH or R1 N ANGLE R2 where R1 and R2 can be linear radicals such as -CH3 or -CH2-CH3 or can be represented by a ring such as that of piperidine, methyl-2-piperidine, piperazine, morpholine, pyrrolidine, methyl-4-piperidine, N-phenyl-piperazine, N-p-methoxy-phenyl-piperazine, N-methyl-4-piperazine, N-p-chlorophenyl-piperazine or hexamethyl-eneimine or ethylamino-ethyl-amine. These compounds have neurotrope, anti-inflammatory and normo-lipid activity. |
