| 主权项 |
1. A method for inducing hair growth in a subject, comprising administering to a subject in need thereof a therapeutically effective amount of a compound of Formula (I): or a stereoisomer thereof; wherein
R1 is hydrogen or RlaC(O)-;R2 is hydrogen or R2aC(O)-;R3 is hydrogen or R3aC(O)-;R1a, R2a and R3a are independently C1-C10 alkyl, C3-C8 cycloalkyl, or aryl, wherein each of C1-C10 alkyl, C3-C8 cycloalkyl, or aryl may be unsubstituted or have one or more substituent groups; andR4and R5a are independently C1-C10 alkyl, C3-C8 cycloalkyl, or aryl, wherein each of C1-C10 alkyl, C3-C8 cycloalkyl, or aryl may be unsubstituted or have one or more substituent groups;wherein the one or more substituent groups are selected from the group consisting of:
(A) OH, NH2, SH, CN, CF3, NO2, oxo, halogen, unsubstituted alkyl, unsubstituted heteroalkyl, unsubstituted cycloalkyl, unsubstituted heterocycloalkyl, unsubstituted aryl, and unsubstituted heteroaryl, and(B) alkyl, heteroalkyl, cycloalkyl, heterocycloalkyl, aryl, and heteroaryl, substituted with at least one substituent selected from:(i) oxo, OH, NH2, SH, CN, CF3, NO2, halogen, unsubstituted alkyl, unsubstituted heteroalkyl, unsubstituted cycloalkyl, unsubstituted heterocycloalkyl, unsubstituted aryl, and unsubstituted heteroaryl, and(ii) alkyl, heteroalkyl, cycloalkyl, heterocycloalkyl, aryl, and heteroaryl, substituted with at least one substituent selected from:
(a) oxo, OH, NH2, SH, CN, CF3, NO2, halogen, unsubstituted alkyl, unsubstituted heteroalkyl, unsubstituted cycloalkyl, unsubstituted heterocycloalkyl, unsubstituted aryl, and unsubstituted heteroaryl, and(b) alkyl, heteroalkyl, cycloalkyl, heterocycloalkyl, aryl, or heteroaryl, substituted with at least one substituent selected from oxo, OH, NH2, SH, CN, CF3, NO2, halogen, unsubstituted alkyl, unsubstituted heteroalkyl, unsubstituted cycloalkyl, unsubstituted heterocycloalkyl, unsubstituted aryl, and unsubstituted heteroaryl;provided that at least one of R1, R2 and R3 is not hydrogen. |
