PROCEDEU PENTRU PREPARAREA FORMEI CRISTALINE & A HIDROCLORURII DE 2-(4-(2-FUROIL)-PIPERAZIN-L-IL)-4-AMINO-6,7-DIMETOXICHINAZOLINA

摘要

The invention relates to novel and valuable crystalline forms of the hypotensive agent prazosin hydrochloride. The anhydrous alpha -form is preferred because it is relatively non-hygroscopic and hence possesses important advantages in handling and formulation. The polyhydrate form of prazosin hydrochloride is preferred because of its low, uniform rate of dissolution.