THREE CONOTOXIN PEPTIDES, PREPARATION METHODS THEREFOR, AND APPLICATIONS THEREOF

摘要

The present invention provides three novel conotoxin peptides, namely κ-CPTx-btl06, κ-CPTx-btl07 and κ-CPTx-btl08, amino acid sequences thereof being shown as SEQ ID NO: 1, 2 and 3 respectively. The present invention also relates to polynucleotides coding these peptides, constructs, expression vectors and transformed cells containing the polynucleotides, preparation methods for the peptides, and uses in preparation of medicines for inhibiting potassium ion channel currents.