PROCESS OF PRODUCING NOVEL MACROLACTONE DERIVATIVES

摘要

PROCESS OF PRODUCING NOVEL MACROLACTONE DERIVATIVES By protecting the aldehyde group of a macrolide series antibiotics with a cyclic acetal or thioacetal, novel macrolide derivatives can be produced from the macrolide series antibiotics by releasing successively the sugar moieties bonded to the macrolide antibiotics. The novel macrolide derivative obtained by this invention, that is, the derivatives of a macrolide series antibiotics produced by releasing partially or wholly the sugar moieties bonded are useful as intermediates for producing novel macrolide series antibiotics.