TARGETED DELIVERY OF GENES ENCODING INTERFERON

摘要

A molecular complex comprising a gene encoding interferon releasably linked to a conjugate of a nucleic acid binding agent and a ligand which binds to a component on the surface of a cell. In a preferred enbodiment, the gene encodes human IFN- alpha , IFN- beta , or IFN- gamma . The complex can be used to obtain targeted expression of interferon in selected cells either in vivo or in vitro.