PROCESS FOR PREPARING 10-METHYL-2,9- DIOXATRICYCLO (4,3,1,03,7) DECANES

摘要

A process for preparing 10-methyl-2,9-dioxatri-cyclo4,3,1,03,7! decane derivatives is disclosed, wherein a 10-methylen-3-iodomethyl compound of the formula is hydrogenated to obtain a mixture of the corresponding epidermic 10.beta.- and 10.alpha.-methyl-3-iodomethyl compounds, the pure 10.alpha.- and 10.beta.-methyl epimers are separated and recovered from this mixture and are reacted with a secondary amine. Optionally, the substituent in the 4-position of the resulting 10.alpha.- or 10.beta.-methyl-3-aminomethyl compounds are further changed.