发明名称 |
Antitumor antibacterial agents |
摘要 |
An antitumor antibacterial complex referred to as BBM-928 is described which is produced by microbiological fermentation under controlled conditions using a species of actinomycetes. The bioactive components of the complex have pronounced antitumor activity and are moderately to weakly active against gram-positive and acid fast bacteria but practically inactive against gram-negative bacteria and fungi. Based on median survival time, the component designated BBM-928A is substantially more active than mitomycin C by a factor of 10 to 300 fold against intraperitoneally implanted mouse tumors.
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申请公布号 |
US4360458(A) |
申请公布日期 |
1982.11.23 |
申请号 |
US19800122626 |
申请日期 |
1980.03.06 |
申请人 |
BRISTOL-MYERS COMPANY |
发明人 |
KOSHIYAMA, HIDEO;SAKAI, FUMIHIDE;OHKUMA, HIROAKI |
分类号 |
A61K38/00;C07K7/06;(IPC1-7):C07C103/52;C07G7/00;A61K37/00 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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