发明名称 |
5,6,7-TRINOR-4,8-INTER-M-PHENYLENE PROSTAGLANDIN I2 DERIVATIVES |
摘要 |
A compound of the formula <IMAGE> (I) wherein R1 is a pharmaceutically acceptable cation, hydrogen or n-alkyl of 1 to 12 carbon atoms; R2 is hydrogen, acyl of 2 to 10 carbon atoms or aroyl of 7 to 13 carbon atoms; R3 is hydrogen, acyl of 2 to 10 carbon atoms or aroyl of 7 to 13 carbon atoms; R4 is hydrogen, methyl or ethyl; R5 is n-alkyl of 1 to 5 carbon atoms; n is an integer of 0 to 4; A is -CH2-CH2- or trans -CH=CH-; and X is -CH2-CH2- or trans -CH=CH-. The compounds are useful in anti-ulcer, hypotensive and platelet aggregation inhibiting compositions. |
申请公布号 |
AU1060983(A) |
申请公布日期 |
1983.07.28 |
申请号 |
AU19830010609 |
申请日期 |
1983.01.19 |
申请人 |
TORAY INDUSTRIES INC. |
发明人 |
HIROSHI NAGASE;KIYOTAKA OHNO;KAZUHISA MATSUMOTO;SHINTARO NISHIO |
分类号 |
A61K31/34;A61K31/343;A61K31/557;A61P7/02;A61P9/08;A61P43/00;C07C29/124;C07C29/56;C07D307/93;C07D493/04;C07F9/40 |
主分类号 |
A61K31/34 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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