发明名称 |
PYRIDINE-PYRIMIDINONE DERIVATIVE, MANUFACTURE AND MEDICINAL COMPOUND |
摘要 |
The invention relates to new pyridine-pyrimidinone derivatives corresponding to the following general formula <IMAGE> (I) wherein R1 represents linear C1-6 alkyl or cycloalkyl and R2 represents linear C1-6 alkyl or R1 and R2 together with the nitrogen atom form a pyrrolidine or piperidine ring; Alk represents a linear alkylene chain C1-6; Q represents a benzene ring, furan ring, thiophene ring or thiazole ring; X represents oxygen, Y is a single bond and m is 2, 3 or 4 when Q represents benzene; X represents methylene, Y represents sulfur and m is 2 or 3 when Q is furan, thiophene or thiazole; and R3 represents a hydrogen atom or a lower alkyl group. These compounds show improved H2-antagonistic activity. |
申请公布号 |
JPS59163385(A) |
申请公布日期 |
1984.09.14 |
申请号 |
JP19840031340 |
申请日期 |
1984.02.20 |
申请人 |
RUUTOBITSUHI HOIMAN UNTO CO GMBH |
发明人 |
HERUMUUTO SHIKUANEIDAA;PIITAA MAASUDOOFU;SHIYUTEFUAAN POSUTEIUSU;IISHIYUTOBAAN ZEERENII;RORUFU HAATAA;HEEBETO HANSEN;KURUTO HENINGU AARENZU |
分类号 |
C07D295/08;C07D213/55;C07D307/38;C07D401/06;C07D405/14;C07D409/14;C07D417/14 |
主分类号 |
C07D295/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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