发明名称 |
Semi-synthesis of human insulin |
摘要 |
A process for preparing a B30-threonine-insulin which comprising reacting a des-B30-insulin with an excess amount of threonine derivative in the presence of an enzyme specifically acting on the basic-amino-acid carbonyl in peptide bondings.
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申请公布号 |
US4511505(A) |
申请公布日期 |
1985.04.16 |
申请号 |
US19830500915 |
申请日期 |
1983.06.03 |
申请人 |
SHIONOGI & CO., LTD. |
发明人 |
MORIHARA, KAZUYUKI;OKA, TATSUSHI;TSUZUKI, HIROSHIGE |
分类号 |
C12P21/02;C07K14/62;C12P21/04;(IPC1-7):C07C103/52 |
主分类号 |
C12P21/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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