摘要 |
Novel process for the preparation of the R enantiomer of (trimethylsilyl)methyl 2-[4-(3,5-dichloropyridyl-2-oxy)phenoxy]- propionate of the formula <IMAGE> which consists in reacting 4-(3,5-dichloropyridyl-2-oxy)phenol of the formula <IMAGE> with the S enantiomer of (trimethylsilyl)methyl 2-tosyloxypropionate of the formula <IMAGE> at temperatures between 50 DEG C and 120 DEG C in the presence of an acid-binding agent and in the presence of a diluent. |