WATER-SOLUBLE EXTRACT FROM NONPATHOGENIC AEROBIC CORYNEBACTERIA, PRODUCTION THEREOF AND COMPOSITIONS CONTAINING THE EXTRACT

摘要

A water-soluble extract from nonpathogenic aerobic corynebacteria such as Corynebacterium equi Ko-85 strain, the water soluble extract generally having a protein content (calculated as Bovine Serum Albumin) of 3.9 to 5.5 mg/ml, a sugar content (calculated as glucose) of 0.41 to 0.52 mg/ml, and an isoelectric point of 3.75 to 3.80, the ratio of the optical density of the extract at 260 nm to that at 280 nm being from 1.56 to 1.62.
Such extracts have shown anti-allergic, anti-cancer, and immunopotentiative effects and can be particularly useful as an anti-allergic agent; they have low toxicity and are satisfactory for use as medicaments.