PROCESS FOR THE PREPARATION OF THE POTASSIUM SALT OF PHOSPHOENOLPYRUVIC ACID

摘要

PCT No. PCT/US82/00402 Sec. 371 Date Aug. 30, 1982 Sec. 102(e) Date Aug. 30, 1982 PCT Filed Mar. 29, 1982 PCT Pub. No. WO83/03412 PCT Pub. Date Oct. 13, 1983.The potassium salt of phosphoenolpyruvic acid (PEP-K), used as a phosphorylation agent particularly in enzymatic reactions, is prepared by a process which consists of two steps, namely the treatment of a halopyruvic acid with a trialkyl phosphite and the hydrolysis of the dialkyl phosphate of enolpyruvic acid thus formed in an aqueous medium and in the presence of potassium hydroxide.