| 摘要 |
<p>Processes for preparing compounds of the formula: < IMG > wherein B is a moiety having the formula: < IMG > or < IMG >; R is mono- or dihalo, amino, nitro, cyano, hydroxy, trifluoromethyl, mercapto, lower alkyl, lower alkoxy, alkanoyl, cycloalkyl of 4-7 carbon atoms, carboxy, loweralkoxycarbonyl, mono- or di-lower alkyl substituted amino, alkanoylamino, lower alkyl thio, lower alkylsulfonyl, sulfamoyl, lower alkyl substituted sulfamoyl, phenyl or phenyl substituted with halo, lower alkyl, lower alkoxy, trifluoromethyl, hydroxy, amino, cyano or nitro; X is SO2, SO, S or C=O; and A is an amine selected from the group < IMG > , or < IMG >, < IMG > wherein R1 is hydrogen or R2CH2 wherein R2 is mono- or diloweralkylamino, mono- or di-N-lower alkylaminoloweralkyl, (2-furyl)methylamino, benzylamino, lowercycloalkylamino, 1-pyrrolidinyl, 1-piperidinyl, 1-hexahydroazepinyl, 1-octa-hydroazocinyl, 3-thiazolidinyl, 4-morpholinyl or 4-thiomor-pholinyl; R3 is hydrogen or (1-piperidinyl)methyl with the proviso that when R3 is (1-piperidinyl)methyl, R1 is hydrogen; n is 1 to 4, and the pharmacologically acceptable salts thereof.</p> |
