发明名称 2,5-DIMETHYLPYRROLE DERIVATIVE, MANUFACTURE AND USE
摘要 2,5-Dimethylpyrrole derivatives of the formula I <IMAGE> (I) in which R denotes alkyl which is substituted by -NH2, acylamino of the formula -NH-CX-R1 or by an optionally substituted heterocycle having 1 hetero member; or denotes an optionally substituted heterocycle having 1 member, and X and R1 have the meanings given and their pharmacologically acceptable acid addition salts, their preparation by reaction of amines of the formula II R-NH2 (II) with acetonylacetone or by acylating N-aminoalkyl-2,5-dimethylpyrroles, and their use as pharmaceutical active compounds.
申请公布号 JPS6233152(A) 申请公布日期 1987.02.13
申请号 JP19860178997 申请日期 1986.07.31
申请人 CASSELLA AG 发明人 GERUHARUTO TSUOORERU;RUUDEI BAIERURE;URUZURA SHINTORERU;RUDORUFU EEBERUHARUTO NITSUTSU;PIERO MARUTORANA
分类号 A61K31/40;A61K31/55;A61P25/28;C07D207/32;C07D207/325;C07D207/327;C07D403/04;C07D417/04 主分类号 A61K31/40
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